| Customization: | Available |
|---|---|
| CAS No.: | 78214-41-2 |
| Formula: | C3h7o* |
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| Name | Hydroxypropyl cellulose |
| Synonyms | Klucel |
| Molecular Structure | |
| CAS Registry Number | 9004-64-2 (78214-41-2) |
Low-substituted hydroxypropyl cellulose (L-HPC) is mainly used as a tablet disintegrator and binder. The characteristics of using low-substituted hydroxypropyl cellulose (L-HPC) as a binder and disintegrator are: easy to press and form, and strong applicability. For tablet binder, 5~20% is generally added when wet granulated, 5~20% is used when powder is directly pressed into tablet, and 2~10% is used as tablet disintegrator, generally 5%, both internal and external can be added, depending on the specific prescription.
Low-substituted hydroxypropyl cellulose (L-HPC) can also be used as a food additive, used as emulsifier, stabilizer, suspension aid, thickener, film forming agent in the food industry, used in the manufacture of beverages, pastries, jam, etc., but also used in the daily chemical industry, used as cream, shampoo, emulsion and other cosmetics manufacturing.
This product is a low-substituted hydroxypropyl cellulose ether, which is a multi-purpose non-ionic cellulose derivative, mainly used as a solid preparation disintegration and binder. Due to the large surface area and porosity of its powder, it can absorb water and expand rapidly. When used in tablets, the tablets can disintegrate rapidly. It can significantly increase the hardness of the tablet without affecting the disintegration, thus accelerating the dissolution of the drug and improving the bioavailability. The dosage of this product is generally about 2-5%, which can be used in the production of tablets in the wet process, and can also be added with external or internal and external effects.
A.Top crack problem is a typical problem in the pressing process. Many reports indicate that the top crack is caused by excessive mold wall residue during the pressing process. Low replacement hydroxypropyl cellulose can reduce the resistance of mold wall residue and demoulding resistance in the process of tablet pressing.
B. LH-11 is a multi-fiber model, which is also the best anti-top cracking effect, and its fibers are interwoven to effectively prevent top cracking.
C. Compared with the three super disintegrators (sodium carboxymethyl starch, crosslinked sodium carboxymethyl cellulose, crosslinked POvidone). The low substituted hydroxypropyl cellulose has certain advantages in the water absorption rate and water absorption, and it will not gel, and there will be no "pockmarked" phenomenon after the tablet stress is removed.
D. Because the low-substituted hydroxypropyl cellulose is prepared by etherization of high-quality wood pulp, it is chemically inert and has high compatibility with apis in preparations, and is mostly used in cardiovascular system and digestive system drugs in consistency evaluation prescription screening.
Executive standard: CP2020, USP
Functional use: disintegrators of tablets and capsules, tablet adhesives
Product category: Pharmaceutical excipients Product properties:
CAS number: 9004-64-2/78214-41-2
Packaging specifications: 25kg/ drum; 25kg/ bag
FAQ
Question 1: Can I get samples?
Answer: Yes,you can get free samples of our most products,
while the courier cost will be borne by the buyers.
Question 2: What's your MOQ?
Answer: For a express delivery order,the MOQ is usually 100 g~1 kg;
for an air transport order or sea delivery order ,the MOQ is usually 25 kgs.
Question 3: What's your delivery time?
Answer:
Orders shipped by express delivery,the delivery time is usually 5~7 working days;
Orders shipped by air transport,usually around 7~10 working days;
Orders shipped by sea , usually around 2~3 working weeks.
Question 4: What are the different payment methods?
Answer: We usually accept T/T, L/C and Western Union.
Question 5: How do you treat quality complaint?
We take quality very seriously, it is one of the founding principles of our business.
If the quality problem actually exists, we will replace with qualified goods or refund the money.
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