Customization: | Available |
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Type: | O-Phospho-L-Serine |
Chemical Character: | Acidity |
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Name | O-Phospho-L-serine |
Synonyms | L-2-Amino-3-hydroxypropanoic acid 3-phosphate; L-Serine monophosphoric acid |
Molecular Structure | |
Molecular Formula | C3H8NO6P |
Molecular Weight | 185.07 |
CAS Registry Number | 407-41-0 |
EC Number | 206-986-0 |
The main uses of O-Phospho-L-serine include:
1. The role of metabolic glutamate receptors: O-Phospho-L-serine is a direct precursor substance in the synthesis of L-serine and also an agonist of type III metabolic glutamate receptors (mGluR4, mGluR7, mGluR8), with no affinity for type I metabolic glutamate receptors. In addition, it is also an antagonist of mGluR1 and mGluR2.
2. The role of NMDA receptors: O-Phospho-L-serine is a competitive antagonist of NMDA, which means it can bind to NMDA receptors, thereby affecting the transmission of neural signals and the release of neurotransmitters.
These characteristics make L-O-phosphoserine potentially valuable in neuroscience research, especially in the study of neural signal transduction, neurotransmitter release, and neuroprotection. In addition, due to its specific biological activity, L-O-phosphoserine may also serve as a potential target in drug development, particularly in the treatment of neurological disorders.
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