Customization: | Available |
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Type: | 5-Chlorothiophene-2-Carboxylic Acid |
Chemical Character: | Acidity |
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Name | 5-Chlorothiophene-2-carboxylic acid |
Synonyms | 5-Chloro-2-thiophenecarboxylic acid |
Molecular Structure | |
Molecular Formula | C5H3ClO2S |
Molecular Weight | 162.59 |
CAS Registry Number | 24065-33-6 |
Melting point | 146-150 ºC |
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2-chlorothiene-5-formic acid is a pharmaceutical intermediate, which can be used to prepare the intermediate 5-chlorothiene-2-formyl chloride of rivaroxaban. Rivaroxaban, also known as Rivaroxaban in English, is a new oral anticoagulant drug with long-term efficacy for the prevention and treatment of venous thrombosis through oral absorption, with a wide therapeutic range and without routine coagulation function monitoring. The world's first direct Factor Xa inhibitor developed for Bayer was approved by the U.S. Food and Drug Administration (FDA) in 2011.
2-chlorothiophene-5-formic acid white solid powder, livestock anti-inflammatory antibacterial drug, mainly used in the treatment of coccidiosis (cecal coccidiosis) in chickens, rabbits, sheep, chicken cholera and typhoid disease.It is an intermediate of the drug rivaroxaban for use in adult patients undergoing elective hip or knee replacement surgery to prevent venous thrombosis (VTE); Intermediate of rivaroxaban.
2-chlorothiene-5-formic acid is often used as an intermediate in organic synthesis, especially in the preparation of thiophene compounds. It can also be used as dye, photosensitizer, fluorescence analysis reagent and so on.
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