| Customization: | Available |
|---|---|
| CAS No.: | 1571-30-8 |
| Formula: | C10h6no3 |
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| Name | 8-Hydroxy-2-Quinolinecarboxylicacid |
| Molecular Structure | |
| Molecular Formula | C10H6NO3 |
| Molecular Weight | 188.16 |
| CAS Registry Number | 1571-30-8 |
| SMILES | C1=CC(=NC2=C(O)C=CC=C12)C([O-])=O |
| InChI | 1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)/p-1 |
| InChIKey | UHBIKXOBLZWFKM-UHFFFAOYSA-M |
| Boiling point | 426.739°C at 760 mmHg (Cal.) |
|---|---|
| Flash point | 211.884°C (Cal.) |
Appearance:
8-hydroxyquinolin-2-carboxylic acid is usually yellow powder or yellow crystalline solid.
Solubility: It is soluble in water, but also soluble in some organic solvents, such as ethanol, acetone and chloroform.
The main uses of 8-hydroxyquinoline
Used as a pharmaceutical intermediate, it is the raw material for synthesizing keroxylenin, chloroiodoquinoline, pumezmin, and is also an intermediate of dyes and pesticides. It is an intermediate of halogenated quinoline antiamoeba drugs, including quiniodoform, chloroiodoquinoline, diiodoquinoline, etc. These drugs play an anti-amoeba effect by suppressing intestinal symbiotic bacteria, and are effective against amoebic dysentery, but have no effect on extrenteral amoeba. It has been reported abroad that this class of drugs can cause subacute spinal optic neuropathy, so the drug has been banned in Japan and the United States, and the disease caused by diiodoquinoline is less common than chloroiodoquinoline. 8-hydroxyquinoline is also an intermediate of dyes and pesticides. Its sulfate and copper salt are excellent preservatives, disinfectants and anti-mildew agents. It is a complexometric indicator for chemical analysis.
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