| Customization: | Available |
|---|---|
| CAS No.: | 68399-76-8 |
| Formula: | 2(C5h3n2o4).Zn.2(H2O) |
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| Name | Orotic acid zinc salt dihydrate |
|---|---|
| Molecular Structure | |
| Molecular Formula | 2(C5H3N2O4).Zn.2(H2O) |
| Molecular Weight | 411.59 |
| CAS Registry Number | 68399-76-8 |
| EINECS | 269-988-0 |
Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.
Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD). Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.
Oroticacid(zinc), a precursor of pyrimidine nucleotide and RNA biosynthesis, is released from mitochondrial dihydrooriotic dehydrogenase (DHODH) and converted to UMP by cytoplasmic UMP synthase. Oroticacid(zinc) is a measure used in routine neonatal screening for urea cycle abnormalities. Oroticacid(zinc) can cause hepatic steatosis and hepatomegaly in rats.
Zinc can promote the metabolism and repair of skin cells, reducing skin inflammation and allergic reactions.
Promoting growth and development: Zinc is an indispensable element in the process of human growth and development, and is involved in the synthesis of human proteins and nucleic acids.
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