| Customization: | Available |
|---|---|
| CAS No.: | 473-98-3 |
| Formula: | C30h50o2 |
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| Name | Betulin |
| Synonyms | Lup-20(29)-ene-3b,28-diol |
| Molecular Structure | |
| Molecular Formula | C30H50O2 |
| Molecular Weight | 442.72 |
| CAS Registry Number | 473-98-3 |
| EINECS | 207-475-5 |
| Melting point | 256-257 ºC |
|---|
This product is white crystalline powder solubility: soluble in ethanol, and benzene, slightly soluble in cold water,etc.
Betulin has anti-inflammatory, antiviral, inhibiting protein dissolution in hair fiber, improving the luster of damaged hair, promoting hair growth and other activities. It can be used in food, cosmetics, medicine and other industries.
Pharmaceutical industry: Betulin is mainly used as pharmaceutical intermediates, and betulin and its derivatives have shown great potential as biologics in HIV and cancer treatment. At the same time, it is used to relieve cough and expectorate, treat allergic rhinitis, insomnia, depression, etc.
Food industry: There are studies on its use as a preservative in meat products.
Cosmetics industry: Betulin's inhibition of collagenase activity and proliferation of skin cells show that it has a strong anti-aging effect and can be used for skin conditioning, smooth skin, and prevention of chapping. It is also a good external osmotic aid.
Daily chemical industry: In hair products, birch brain can reduce protein dissolution in hair fibers, improve damaged hair luster, and promote hair growth.
1. Inhibiting the formation of melanin betulin can be used as a natural and safe herbal phytoestrogen without side effects. It can inhibit the synthesis of melanin in A375 cells through p38-MAPK signaling pathway, reduce skin hyperpigmentation, improve the impact of melasma on the appearance of patients, and reduce the incidence of uterine cancer and breast cancer without being affected by side effects.
2. Betulin has good pharmacological effect in anti-hyperlipidemia and can reduce blood cholesterol and triacylglycerol at the same time. In addition, it can inhibit the function of cholesterol regulatory element binding protein (SREBP), thereby affecting cholesterol metabolism, significantly reducing the levels of triglycerides, fatty acids and cholesterol in the blood, improving hyperlipidemia and resistance in obese patients, and achieving significant therapeutic effect on type 2 diabetes.
3. Hepatoprotective effect Betulin has certain therapeutic effects on rats with alcoholic fatty liver disease, which can significantly improve the fatty degeneration and necrosis of liver tissue caused by alcohol, inhibit the damage of liver tissue caused by alcohol-induced lipid peroxidation, and have a good therapeutic effect on alcoholic liver injury.
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