Customization: | Available |
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CAS No.: | 328-42-7 |
Formula: | C4h4o5 |
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Name | Oxalacetic acid |
Synonyms | 2-Oxosuccinic acid; Oxobutanedioic acid |
Molecular Structure | |
Molecular Formula | C4H4O5 |
Molecular Weight | 132.07 |
CAS Registry Number | 328-42-7 |
EC Number | 206-329-8 |
Melting point | 161 ºC |
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Water solubility | soluble |
White to off-white powder.
Oxaloacetic acid is another novel anti-aging ingredient from Herb Nutritionals Co., Ltd. Oxaloacetate is the ionized type of oxaloacetic acid, or we might say oxaloacetic acid is in the form of its conjugate base oxaloacetate that is central to metabolic process and can be found in every cell of the body and it is an intermediate substrate from the Krebs Cycle (Citric Acid Cycle) as well as in Gluconeogenesis.
Oxaloacetic acid (OAA), with CAS as 328-42-7, is a white to off-white crystalline powder and has many other names, such as Oxobutanedioic acid, 2-Oxosuccinic acid, Ketosuccinic acid, 3-carboxy-3-oxopropanoic acid,etc.
The key benefits of oxaloacetic acid can be summarized as anti-aging, increase lifespan (life extension), brain health, blood sugar regulation, and energy production. Some Experiments have shown oxaloacetic acid to provide powerful protection against the effects of cancer, stroke, and traumatic brain injury.
The function and use of oxaloacetate
A. Function
1. Sugar metabolism
As the starting material of the tricarboxylic acid cycle (TCA), it binds with acetyl CoA to generate citric acid, which promotes the complete oxidation and decomposition of glucose. The key intermediate product of gluconeogenesis promotes the conversion of pyruvate, lactate, and gluconic amino acids into glucose.
2. Lipid metabolism
Through the citric acid pyruvate transport system, acetyl CoA in mitochondria is transferred to the cytoplasm to participate in fatty acid synthesis. Fatty acid beta oxidation products (such as succinyl CoA) need to bind with oxaloacetate to enter the TCA cycle metabolism.
3. Amino acid metabolism
Generate aspartic acid through transamination and participate in the deamination process of amino acids in the purine nucleotide cycle. The synthesis and degradation of aspartic acid amino acids such as Lys and Thr depend on oxaloacetate.
4. Nucleotide metabolism
As a precursor of aspartic acid (Asp), it directly participates in the synthesis of purine nucleotides (such as IMP) and pyrimidine nucleotides (such as UMP). The degradation products of pyrimidine bases (acetyl CoA, succinyl CoA) are associated with oxaloacetate through the TCA cycle.
B. Purpose:
1. Plastic processing: As an anti-static agent, release agent, and lubricant for polyolefin and PVC plastics.
2. Dyes and inks: used as pigment dispersants and ink additives to improve material uniformity.
3. Neuroprotection: Relieve neurotoxicity by consuming glutamine, used for the treatment of epilepsy, brain injury, etc.
4. Antitumor potential: Inducing tumor cell apoptosis has become a key component in anti-cancer drug research.
5. Metabolic intervention: Simulate carbohydrate metabolism signals, assist in weight loss, and inhibit glucose and lipid metabolism disorders.
6. Energy transfer: Participate in the malate aspartate shuttle and assist in the transport of cytoplasmic NADH to mitochondria.
7. Photosynthesis regulation: Enhance photosynthetic oxygen release rate in plants and promote chloroplast energy conversion efficiency.
Test Items | Specifications |
Appearance | White to off-white powder |
Infrared Spectrum | Conforms |
Solubility | 2%solution in water is cear and complete |
Assay(Titration) | ≥98.0% |
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