| Customization: | Available |
|---|---|
| CAS No.: | 67-52-7 |
| Formula: | C4h4n2o3 |
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| Name | Barbituric acid |
| Synonyms | 2,4,6(1H,3H,5H)-Pyrimidinetrione; 2,4,6-Trihydroxy-1,3-diazine; Malonylurea |
| Molecular Structure | |
| Molecular Formula | C4H4N2O3 |
| Molecular Weight | 128.09 |
| CAS Registry Number | 67-52-7 |
| EINECS | 200-658-0 |
| Melting point | 248-255 ºC |
|---|---|
| Water solubility | 142 g/L (20 ºC) |
Used as organic synthesis raw materials, medicine, plastics and dye intermediates. It is an intermediate of barbiturate, vitamin B12 and other drugs, and can also be used as a polymerization catalyst and the preparation of benzimidazolone organic pigments. It can also be used as a colorimetric reagent for the determination of glycolaldehyde and polypentose.
It is used as a pharmaceutical intermediate to synthesize barbiturate, vitamin B12 and other drugs, and is also used as a polymerization catalyst and raw material for making dyes. Barbiturate is the parent compound of barbiturates. Unsubstituted barbiturate has no hypnotic effect.
The mechanism of action of barbiturates is basically the same, which acts on different levels of the central nervous system and has non-specific inhibitory effect. The mechanism of sedative hypnosis may be related to the selective inhibition of the activation system in the thalamo-reticular, thus blocking the conduction of excitations to the cerebral cortex. Its anticonvulsant effect is achieved by inhibiting synaptic transmission in the central nervous system and increasing the threshold of electrical stimulation in the motor area of the cerebral cortex.
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