Product Description
beta-Diphosphopyridine nucleotide
| Name |
β-Diphosphopyridine nucleotide |
| Synonyms |
β-Nicotinamide adenine dinucleotide; beta-DPN; beta-NAD |
| Molecular Structure |
|
| Molecular Formula |
C21H27N7O14P2 |
| Molecular Weight |
663.43 |
| CAS Registry Number |
53-84-9 |
| EC Number |
200-184-4 |
Chemical Property/Description:
White powder.
beta-Diphosphopyridine nucleotide also known as diphosphopyridine nucleotide (abbreviated DPN), or codehydrogenase I or Coenzyme I. In mammals, there are two states of oxidation (NAD+) and reduction (NADH). The oxidation (NAD+) has the maximum ultraviolet absorption spectrum at 260nm. By various deaminases, it accepts a hydrogen atom and an electron from the substrate and becomes a reduced (NADH). Maximum absorption occurs at 340nm. Beta-nicotinamide adenine dinucleotide is used as a coenzyme in REDOX reactions, as a donor of the ribose portion of ADP in the ribosylation of ADP, and as a precursor of the second messenger molecule cyclic ADP ribose. Beta-nicotinamide adenine dinucleotides also act as substrates for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
Main Uses:
Use:
1. Energy metabolism and cellular function
2. Anti aging and DNA repair
3. Neuro and cardiovascular protection
4. Immune regulation and disease treatment
5. Skin Health and Metabolic Regulation
β-Nicotinamide adenine dinucleotide is involved in many physiological activities such as cell metabolism, energy synthesis, cell DNA repair, and plays an important role in the body's immune capacity.
In a healthy state, the concentration of β-Nicotinamide adenine dinucleotide in the human body is stable, and the normal function of all cells is maintained. The concentration of β-Nicotinamide adenine dinucleotide in the body determines the process and degree of cell aging, and the decrease of concentration will accelerate the process of cell aging. Studies have shown that NAD+ has a protective effect on renal infarction caused by ischemic surgery, and can significantly reduce the levels of serum urea nitrogen and creatinine. NAD+ has a protective effect on renal tubule injury caused by ischemic surgery. NAD + (nicotinamide adenine dinucleotide, Nicotinamideadeninedinucleotide, NAD +) can effectively protect the kidney ischemia caused by kidney damage, NAD + in the preparation of drug prevention and treatment of renal ischemic injury has important application value.
In addition, β-Nicotinamide adenine dinucleotide has a certain application in the preparation of inflammatory pain drugs. NAD+ is involved in the regulation of inflammatory pain induced by formalin and complete Fredrin adjuvant (CFA) through NAD+ dependent deacetylases SIRT1 and SIRT2. SIRT1 and SIRT2 participate in the inhibitory effect of NAD+ on inflammatory pain through different mechanisms, so as to achieve analgesic effect on inflammatory pain.
1.β-Nicotinamide adenine dinucleotide is a kind of coenzyme drug. Clinically, it is mainly used for the auxiliary treatment of coronary heart disease, which can improve chest tightness, angina pectoris and other symptoms. The side effects were dry mouth, dizziness, nausea and so on.
2.Participate in energy metabolism and material metabolism in the body, which is conducive to cell repair and renewal. It is used for the treatment of coronary heart disease, myocarditis, leukopenia and so on.
Specification
| Testing Items |
Specifications |
| Appearance |
White powder |
| Water |
≤8.0% |
| Sodium Contents |
≤1.0% |
| PH |
2.0-5.0 |
| Purity (HPLC) |
≥99.0% |
| Assay of β-NAD(on dried basis) |
≥99.0% |
| Heavy Metal |
| Lead(Pb),ppm |
≤0.5 |
| Arsenic(As), ppm |
≤0.5 |
| Cadmium(Cd),ppm |
≤0.5 |
| Mercury(Hg), ppm |
≤0.5 |
| Microbiological Control |
| Total Plate Count |
≤750cfu/g |
| Yeast and Mould |
≤100cfu/g |
| Salmonella |
Negative |
| E.Coli |
Negative |
| Staphylococcus Aureus |
Negative |
Detailed Photos
FAQ
FAQ
Question 1: Can I get samples?
Answer: Yes,you can get free samples of our most products,
while the courier cost will be borne by the buyers.
Question 2: What's your MOQ?
Answer: For a express delivery order,the MOQ is usually 100 g~1 kg;
for an air transport order or sea delivery order ,the MOQ is usually 25 kgs.
Question 3: What's your delivery time?
Answer:
Orders shipped by express delivery,the delivery time is usually 5~7 working days;
Orders shipped by air transport,usually around 7~10 working days;
Orders shipped by sea , usually around 2~3 working weeks.
Question 4: What are the different payment methods?
Answer: We usually accept T/T, L/C and Western Union.
Question 5: How do you treat quality complaint?
We take quality very seriously, it is one of the founding principles of our business.
If the quality problem actually exists, we will replace with qualified goods or refund the money.
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