| CAS No.: | 531-75-9 |
|---|---|
| Formula: | C15h16o9 |
| EINECS: | 208-517-5 |
| Classification: | Monosaccharides |
| Appearance: | Liquid |
| Grade Standard: | Food Grade |
| Customization: |
|---|
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| Name | Esculin |
| Synonyms | 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one; 6,7-Dihydroxycoumarin 6-glucoside; 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one |
| Molecular Structure | |
| Molecular Formula | C15H16O9 |
| Molecular Weight | 340.29 |
| CAS Registry Number | 531-75-9 |
| EINECS | 208-517-5 |
| Melting point | 203-205 ºC |
|---|---|
| alpha | -88 º (c=2,dioxane/water1:1) |
| Water solubility | MODERATELY SOLUBLE |
Esculin is a coumarin-like compound extracted from the dry bark or bark of Carpinus ash, which is an effective component of traditional Chinese medicine Aesculus. It is a white crystalline powder at room temperature with a slightly bitter smell. aesculin and aesculetin are effective in the treatment of bacillary dysentery and tracheitis.
In addition, it also has anti-inflammatory, antibacterial, anticoagulant, analgesic and other activities, and has significant diuretic effect on mice. Aldose reductase can inhibit the lens of the rat eye, is a growth inhibitor of Bacillus subtilis, and has an inhibitory effect on chemical to cancer.
For content determination/identification/pharmacological experiments, etc.
Pharmacological effect: Esculin has anti-inflammatory, antibacterial, anticoagulant, analgesic and other activities, and has significant diuretic effect on mice. Esculin can inhibit the lens of the rat eye, is a growth inhibitor of Bacillus subtilis, and has an inhibitory effect on chemical to cancer.
A coumarin glycoside that has antioxidant activity and prevents chemically induced carcinogenesis. Used in microbiology for the isolation and identification of enterococcus (Group D streptococcus).
Esculin can promote urine excretion and diuresis, analgesia, anticonvulsant, aesculotin can promote uric acid excretion, the mechanism of action is excitatory sympathetic nervous system, inhibit renal uric acid reabsorption and so on; Esculin has a diuretic effect. Esculin has obvious diuretic effect, while Esculin have obvious anti-platelet aggregation effect. Esculin is an important anticoagulant.
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