Urolithin B CAS 1139-83-9 Nsc 94726 3-Hydroxyurolithin 7-Hydroxy-3, 4-Benzocoumarin

• CAS No.: 1139-83-9
• Formula: C13h8o3
• EINECS: 616-396-9
• Certification: CCIC, CIQ, ISO
• Purity: 90%~99%
• Type: Sodium Hexametaphosphate
• Model NO.: SUREST-172
• Grade Standard: Food Grade
• Molecular Weight: 212.20
• Shelf Life: 2 Years
• Stock: Available
• Density: 1.395±0.06 g/cm3 (20 ºC 760 Torr)
• Melting Point: 255-256 ºC
• Solubility: Practically Insoluble (0.093 G/L) (25 ºC)
• Transport Package: 1kg/Bag or 25kg/Drum
• Specification: 98%min
• Trademark: Surest
• Origin: China
• HS Code: 2914400090
• Production Capacity: 1000 Tons Yearly

Product Description

Urolithin B
 

Name	Urolithin B
Synonyms	3-Hydroxy-6H-dibenzo[b,d]pyran-6-one; 3-Hydroxy-6H-benzo[c]chromen-6-one; 3-Hydroxydibenzo-alpha-pyrone; 3-Hydroxyurolithin; 7-Hydroxy-3,4-benzocoumarin; NSC 94726
Molecular Structure
Molecular Formula	C13H8O3
Molecular Weight	212.20
CAS Registry Number	1139-83-9

Properties

Solubility	Practically insoluble (0.093 g/L) (25 ºC), Calc.^*
Density	1.395±0.06 g/cm^3 (20 ºC 760 Torr), Calc.^*
Melting point	255-256 ºC^**

^*	Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2017 ACD/Labs)
^**	Garazd, Ya. L.; Chemistry of Natural Compounds (Translation of Khimiya Prirodnykh Soedinenii) 2003, V38(5), P424-433.

Chemical Property:
White powder.

Main Uses:
1. Toxicological properties: urolithin-B has shown certain toxicity in animal experiments, but is relatively safe in clinical use.

2. Clinical use: urolithin-B is mainly used to treat gram-negative bacterial infections, such as urinary system infection, respiratory system infection, etc.

3. Use restrictions: The use of urolithin-B is limited because it may cause some adverse reactions and drug interactions.

4.Urolithin B is one of the gut microbial metabolites of ellagitannins, which has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by decreasing phosphorylation and degradation of IκBα.

5.Urolithin B inhibits phosphorylation of JNK, ERK and Akt, and enhances phosphorylation. Urolithin B is also a regulator of skeletal muscle mass.

 

Detailed Photos