Parthenolide CAS 20554-84-1 (-) -Parthenolide Ptl

• CAS No.: 20554-84-1
• Formula: C15h20o3
• EINECS: N/a
• Classification: Aromatic Alcohol
• Appearance: Powder
• Type: 1°(Primary Alcohol)
• Model NO.: SUREST-242
• Hydroxyl No.: Monohydroxy
• Stock: Available
• Molecular Weight: 248.32
• Color: Pale Brown
• Melting Point: 115-116 ºC
• Solubility: Soluble in DMSO
• Transport Package: 25kg/Drum
• Specification: 98%min
• Trademark: Surest
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000 Tons Yearly

Product Description

Product Description

 

 

Name	Parthenolide
Molecular Structure
Molecular Formula	C15H20O3
Molecular Weight	248.32
CAS Registry Number	20554-84-1

Properties

Melting point	115-116 ºC

 

Chemical Property/Description:

Parthenolide is a sesquiterpene lactone found in the herb Coreopsis breviglossum. Feverolactone exhibits anti-inflammatory activity by inhibiting NF-κB activation, and feverolactone also inhibits HDAC1 protein without affecting other class I/II HDacs.

Feverfew extract is the flower bud extract of ChryanthemumParthenium, a plant belonging to Tanace-tum of Compositae family. It mainly contains volatile oil (α-pinene), sesquiterpene lactone (parthenlide), sesquiterpene lactone (parthenlide), flavonoids, and the active ingredient is parthenlide. It has analgesic, antitumor, antifungal, antibacterial and migraine pharmacological effects. Often used to treat migraine, but also used to treat arthritis, rheumatism, dysmenorrhea, leukemia and so on.

Main Uses:

Feverfew extract mainly has the effects of analgesia, antipyretic, anti-inflammatory, anti-rheumatism, menstrual regulation and so on. Studies have shown that feverolide inhibits the release of the hormone serotonin, which causes migraines. It also lowers body temperature, regulates menstruation, and has the effect of oxytocin.

Binding to vasohibin 1(angiogenesis inhibitory protein) to form crystals in order to study the mechanism of microtubulin detyrosination inhibition as an inhibitor of nuclear factor-activated B cell (NF-κB) κ-light chain enhancer, as well as an inhibitor of signal transduction and transcriptional activation factor (STAT), To study its effect on the cell adhesion of CD36 binding Plasmodium falciparum infected red blood cells (IECD36) as a lipophilic reagent, and to study its effect on the production of interleukin-13 and interferon-γ by peripheral blood derived CD8+T cells.
 

Detailed Photos