Customization: | Available |
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CAS No.: | 7585-39-9 |
Formula: | C42h70o35 |
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Name | beta-Cyclodextrin |
Synonyms | beta-Cycloamylose; beta-Cycloheptaamylose; beta-Dextrin |
Molecular Structure | |
Molecular Formula | C42H70O35 |
Molecular Weight | 1134.98 |
CAS Registry Number | 7585-39-9 |
EINECS | 231-493-2 |
Melting point | 322.9 ºC (decomp)* |
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* | Song, Le Xin; Bulletin of the Chemical Society of Japan 2007, V80(11), P2185-2195. |
As a new pharmaceutical excipient, β-cyclodextrin is mainly used to increase the stability of drugs, prevent the oxidation and decomposition of drugs, improve the dissolution and bioavailability of drugs, reduce the toxic side effects of drugs, and cover up the odor and odor of drugs. In food manufacturing, it is mainly used to eliminate odors, improve the stability of flavors and pigments, and enhance emulsification and moisture-proof ability. Improve the taste of food, is a good stabilizer and corrective agent for pharmaceutical, food and cosmetics manufacturing industry.
In the food industry, the slow release of food preservatives and preservatives, improve the anti-corrosion effect, extend the shelf life of food, improve the taste of food, in food manufacturing, mainly used to eliminate odor, improve the stability of flavors and pigments, enhance the emulsification ability and moisture-proof ability.It is widely used in the pharmaceutical excipients industry. It is used to increase the stability of drugs, prevent oxidation and decomposition of drugs, improve the dissolution and bioavailability of drugs, reduce the side effects of drugs, and cover up the odor and odor of drugs. In the cosmetics industry, it can prevent cosmetic whitening agents from damaging blood acid oxidation and Browning to improve the whitening effect and reduce irritation.
Widely used in the separation of organic compounds and organic synthesis, but also used as pharmaceutical excipients, food additives and so on. Natural and modified cyclodextrins have been prepared into clathrates with some non-biocompatible drug molecules. It not only increases the biocompatibility of the drug, but also plays a role in slow release.
Carried Standard:CP/USP/EP
Application:
1, the pharmaceutical industry cyclodextrin can effectively increase the solubility and dissolution rate of some poorly water-soluble drugs in water, such as prostaglandin-CD inclusion compounds can increase the solubility of the main drug to make injections. It can also improve the stability and bioavailability of volatile oil of drugs such as Changkang granules; Reduce the undesirable odor or bitterness of drugs such as andrographis paniculata; Reduce irritation and toxic side effects of drugs (such as diclofenac sodium); And to slow the release of drugs (such as berberine hydrochloride) and improve the dosage form.
2, analytical chemical cyclodextrin is a chiral compound, it has the ability to identify and select organic molecules, has been successfully used in a variety of chromatography and electrophoresis methods to separate various isomers and enantiomers. Cyclodextrin can improve the selectivity of the system in electrochemical analysis.
3, the daily chemical cyclodextrin and surfactant together used in shampoo and kitchen cleaning agent can reduce the stimulation of surfactant on the skin; The use of cyclodextrins can also remove oil stains on the fabric; In the dyeing process, the use of cyclodextrin can significantly reduce the initial dyeing rate of the dye, improve the evenness and the amount of color of the fiber.
4, the application of environmental protection cyclodextrin in environmental protection is based on its ability to form a stable envelope with pollutants, thereby reducing environmental pollution. Its unique molecular structure can be used for biological treatment of industrial wastewater. In addition, air fresheners can add cyclodextrins to slowly release gas molecules and extend the duration of the fragrance.
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