Fisetin CAS 528-48-3 3, 3′, 4′, 7-Tetrahydroxyflavone C. I. Natural Brown 1

• Customization: Available
• CAS No.: 528-48-3
• Formula: C15h10o6
• Model NO.: SUREST-175
• Certification: CCIC, CIQ, ISO
• Purity: 90%~99%
• Type: Sodium Hexametaphosphate
• Grade Standard: Food Grade
• Molecular Weight: 663.43
• Shelf Life: 2 Years
• Stock: Available
• Appearance: Yellow
• Water Solubility: Soluble
• Melting Point: 330 ºC
• Transport Package: 1kg/Bag or 25kg/Drum
• Specification: 98%min
• Trademark: Surest
• Origin: China
• HS Code: 2938909090
• Production Capacity: 1000 Tons Yearly

Product Description

Fisetin
 

Name	Fisetin
Synonyms	3,3',4',7-Tetrahydroxyflavone
Molecular Structure
Molecular Formula	C15H10O6
Molecular Weight	286.24
CAS Registry Number	528-48-3
EINECS	208-434-4

Properties

Melting point	330 ºC

Chemical Property:
Yellow powder.


Main Uses:

1. Inhibition of prostaglandin: It can inhibit the formation of prostatic cords in the fibrocytes of 3T3 mice transformed by methylcholanthrene, and the median effective inhibitory concentration (ID50) is 42.0UM.
2. Enzyme inhibition: It has an inhibitory effect on the total sugar reductase of the rat eye lens, and the half effective inhibitory concentration is 10-6M
3. Antispasmodic: In mouse small intestine specimens, the antispasmodic effect of acetylcholine was 166% of that of papaverine. 4. A team of Japanese and American researchers found in animal experiments that urushetin in vegetables and fruits helps improve memory.

The anti-aging mechanism of Fisetin: urushetin can induce autophagy by simulating caloric restriction, a study in 2018 showed that urushetin has the best effect on clearing senescent cells among 10 flavonoids, and its effect exceeds that of resveratrol, curcumin, and catechin.


It is widely found in fruits and vegetables such as strawberries, apples, Onions, cucumbers and so on. It comes from a wide range of sources, is cheap and easy to obtain, and has a wide range of pharmacological activities, such as anti-inflammatory, antioxidant, anticoagulant, antithrombotic, spasmolytic, and treatment of diabetic kidney injury.

In recent years, it has been found that Fisetin can play an anti-tumor role by inhibiting tumor cell proliferation and signal transduction pathway, inducing tumor cell apoptosis, etc., so it has attracted increasing attention.






 

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