| Appearance: | Powder |
|---|---|
| Grade Standard: | Food Grade |
| Shelf Life: | 2 Years |
| Stock: | Available |
| Molecular Weight: | 511.51 |
| Melting Point: | >300°c |
| Customization: |
|---|
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| Name | 1492-18-8 |
| Synonyms | Folinic acid calcium salt; N-(4-(((2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid calcium salt |
| Molecular Structure | |
| Molecular Formula | C20H21N7O7.Ca |
| Molecular Weight | 511.51 |
| CAS Registry Number | 1492-18-8 |
| EINECS | 216-082-8 |
This product is white to yellowish crystalline or amorphous powder, odorless. This product is dissolved in water, almost insoluble in ethanol or ether, and dissolved in 0.1mol/L solution.
1. It is mainly used as an antidote to folate antagonists (such as trimethoprim, etc.), and is often used to prevent serious toxic effects caused by large doses or excessive treatment of
2, for folic acid treatment of the following diseases, such as oral diarrhea, protein-energy malnutrition (malnutrition), pregnancy or infancy caused by megaloblastic anemia is not effective.
3, as an adjunct treatment for colon cancer and rectal cancer.
4. Combined with 5-FU, it is used to treat digestive tract tumors or other 5-FU-sensitive tumors. The combination of high-dose CF and 5-FU (LF regimen) is the basic regimen for the treatment of colon and rectal cancer.
5, used in children leukemia, lymphoma and osteosarcoma and other large dose MTX treatment rescue.
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