Customization: | Available |
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CAS No.: | 7331-52-4 |
Formula: | C4h6o3 |
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Name | (S)-3-Hydroxy-gamma-butyrolactone |
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Molecular Structure | |
Molecular Formula | C4H6O3 |
Molecular Weight | 102.09 |
CAS Registry Number | 7331-52-4 |
Density | 1.24 |
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Boiling point | 98-100 ºC (0.3 mmHg) |
Refractive index | 1.463-1.466 |
Flash point | >110 ºC |
Properties:
(s) -3-hydroxy-gamma-butyrolactone is a colorless liquid, soluble in water, alcohols and other organic solvents, and insoluble in petroleum ether, etc. It is an important organic synthetic intermediate, and an important Chiral Pool. It is mainly used as a key intermediate of the regulator (R) -γ-hydroxy-β-q hydroxybutyric acid [(R)-GABOB], which is used to treat hyperlipidemia; (s)-Oxiracetam is a promoter of brain metabolism and is also synthesized; (s) -3-hydroxy-tetrahydrofuran can be obtained by reducing it, which is an important intermediate of AIDS drugs. The (s) -3-hydroxy-4-bromobutyric acid synthesized from it is a potential stabilizer. Converting it into (s) -5-hydroxymethyl-1, 3-azolin-2-one can obtain the latest generation of antibacterial drugs; In addition, (s) -n-methyl-3-hydroxypyrrole and (R) -n-methyl-3-methylazyl pyrrole also have important physiological activities, and (s) -3-hydroxy-γbutyrolactone can be obtained by simple conversion. Many natural products can also be synthesized from (s) -3-hydroxy-gamma-butyrolactone.
Use:
It is a very important intermediate in organic synthesis and a very important ChiralPool. It is mainly used as a key intermediate of the regulator (R) -γ-hydroxy-β-q hydroxybutyric acid [(R)-GABOB], which is used to treat hyperlipidemia; (s)-Oxiracetam is a promoter of brain metabolism and also a synthetic; (s) -3-hydroxy-tetrahydrofuran can be obtained by reducing it, which is an important intermediate of AIDS drugs. The (s) -3-hydroxy-4-bromobutyric acid synthesized from it is a potential stabilizer. Converting it into (s) -5-hydroxymethyl-1, 3-azolin-2-one can obtain the latest generation of antibacterial drugs; In addition, (s) -N-methyl-3-hydroxypyrrole and (R)-
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