Mebendazole CAS 31431-39-7 5-Benzoyl-2-Benzimidazolylcarbamic Acid Methyl Ester Methyl 5-Benzoyl Benzimidazole-2-Carbamate

• CAS No.: 31431-39-7
• Formula: C16h13n3o3
• EINECS: 250-635-4
• Classification: Mebendazole
• Shape: Powdery
• Grade Standard: Industrial Grade
• Model NO.: SUREST-459
• Source: Mebendazole
• Shelf Life: 2 Years
• Stock: Available
• Molecular Weight: 295.30
• Density: 1.388g/cm3
• Melting Point: 288.5 ºC
• Boiling Point: N/a
• Refractive Index: 1.702
• Flash Point: N/a
• Water Solubility: Insolubie
• Transport Package: 25kg /Barrel
• Specification: 98%min
• Trademark: Surest
• Origin: China
• HS Code: 2933990090
• Production Capacity: 1000 Tons Yearly

Product Description

Product Description

 

Name	Mebendazole
Synonyms	5-Benzoyl-2-benzimidazolylcarbamic acid methyl ester; Methyl 5-benzoyl benzimidazole-2-carbamate
Molecular Structure
Molecular Formula	C16H13N3O3
Molecular Weight	295.30
CAS Registry Number	31431-39-7
EINECS	250-635-4

Properties

Melting point	288.5 ºC

 

Main Uses:

 

Mebendazole is a broad-spectrum deworming drug, which can completely kill the eggs of hookworm and whipworm and partially kill the eggs of roundworm. Mebendazole has a strong affinity for the β-tubulin of worm and can bind to it at a very low concentration. Mebendazole can inhibit the polymerization of its microtubules by affecting the metabolism of carbohydrate and related energy generation of worm, and cause the loss of the epidermal or intestinal cells of worm. It can selectively and irreversibly inhibit the uptake of glucose and other nutrients from the intestinal tract, and eventually lead to the death of the insect. It is suitable for the treatment of human and animal infections caused by whipworm, pinworm, hookworm, tapeworm, strongylodes faecalis, roundworm and other single or multiple worms, but it is not effective for echinococcosis. Bendazole is also an oxidative phosphoric acid uncoupling agent, which can inhibit fumarate reductase in mitochondria and reduce glucose transport, thus affecting ATP production. Mebendazole suspension can inhibit the uptake of glucose by intestinal parasites, resulting in the depletion of glycogen stores and the reduction of adenosine triphosphate formation, but does not affect the glucose level in the blood of the host. Ultrastructural observation showed that the suspension of mebendazole could cause the degeneration of microtubules in the membrane cells and the cytoplasm of intestinal cells, resulting in the accumulation of secretory particles in Golgi, resulting in transport blockage, cytosolysis, complete degeneration of absorption cells, and death of the worm.

 

 

Detailed Photos

 

 

FAQ

 

FAQ
Question 1: Can I get samples?
Answer: Yes,you can get free samples of our most products,
while the courier cost will be borne by the buyers.

Question 2: What's your MOQ?
Answer: For a express delivery order,the MOQ is usually 100 g~1 kg;
for an air transport order or sea delivery order ,the MOQ is usually 25 kgs.

Question 3: What's your delivery time?
Answer:
Orders shipped by express delivery,the delivery time is usually 5~7 working days;
Orders shipped by air transport,usually around 7~10 working days;
Orders shipped by sea , usually around 2~3 working weeks.

Question 4: What are the different payment methods?
Answer: We usually accept T/T, L/C and Western Union.

Question 5: How do you treat quality complaint?
We take quality very seriously, it is one of the founding principles of our business.
 If the quality problem actually exists, we will replace with qualified goods or refund the money.